valuation of liver Aminotransferase Among Type 2 Diabetic Patients Attending Gharyan Central Hospital
Journal ArticleDiabetes mellitus is a growing global health concern, characterized by chronic hyperglycemia, resulting from defective insulin action and secretion, T2DM is frequently associated with abnormalities in the liver function, which may reflect underlying metabolic disturbances and early hepatic involvement. This study aimed to evaluate the levels of liver aminotransferase ( ALT, AST) and ALP in patients with type 2 diabetes in Gharyan central hospital. The finding showed that patients with T2DM had elevated liver enzyme levels, (ALT, AST and ALP were 19%, 15%, 41% respectively), suggesting possible subclinical liver dysfunction. These results highlight the importance of routine liver enzyme assessment in the clinical follow up of individuals with T2DM, as early detection of hepatic abnormalities may improve patient management and reduce the risk of diabetes- related complications.
Mustafa Amran Abdulsalam Saieh, Amna Zawal, (06-2026), ليبيا: مجلة صدى القلم, 1 (2), 23-32
Association Between Serum Vitamin D Levels and Acute Respiratory Tract Infections Among Preschoo
Journal ArticleAbstract Background: Acute respiratory tract infections (ARTIs) remain one of the leading causes of morbidity and Published: June 15, 2026 hospitalization among preschool children worldwide. particularly in low- and middle- income countries. Vitamin D plays a crucial immunomodulatory role in respiratory health by enhancing innate immunity and maintaining epithelial barrier integrity. However, vitamin D deficiency is highly prevalent among children, including those living in sun- rich regions such as Libya. Objectives: This study aimed to assess serum vitamin D levels among preschool children admitted with ARTIs at Gharyan Central Teaching Hospital and to evaluate the association between vitamin D status, disease severity, and recurrence. Methods: A cross-sectional observation study was conducted among 100 preschool children aged 1-6 years admitted with clinically diagnosed ARTIs between January and December 2025. After applying the inclusion and exclusion criteria, 79 eligible participants were included in the final analysis. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured and categorized according to Endocrine Society guidelines. Associations between vitamin D levels, ARTIs severity, and recurrence were analysed using chi-square tests and logistic regression models. Results: Vitamin D deficiency and insufficiency were highly prevalent, affecting 87.3% of the studied children. Although lower vitamin D levels were more frequently observed among children with moderate and severe ARTIs, the association with disease severity was not statistically significant (p=0.115). In contrast, a significant association was identified between low vitamin D levels and recurrent ARTIs (p=0.019). Conclusion: Vitamin D deficiency is highly prevalent among preschool children hospitalized with ARTIs and is significantly associated with recurrent infections. Improving vitamin D status may contribute to reducing the recurrence of ARTIs in this population.
Mustafa Amran Abdulsalam Saieh, نجاح رجب غومة, (06-2026), ليبيا: African Journal of Advanced Pure and Applied Sciences (AJAPAS), 5 (2), 313-322
,Distribution of ABO Blood Groups and Rhesus Factor in Gharyan City,Northwestern Libya
Journal ArticleAbstract Understanding the distribution of ABO and Rh blood types in a population helps genetic research and studies on disease susceptibility associated with blood types. It also helps blood banks efficiently manage donor blood supplies, providing the availability of compatible blood types for transfusions and emergencies. This study was conducted to analyze the distribution of ABO and Rh-D blood groups in Gharyan city, Libya. The statistics suggest that Blood group O (48.73%) is the most frequent, followed by A (36.36%), B (11.61%), and AB (3.28%). A lesser number of the population is Rh-D negative (20.20%), while the majority is Rh-D positive (79.79%). These results could help blood banks manage blood transfusion programs in handling local blood transfusion services. Keywords. ABO Blood Groups, Rh-d Factor, Blood Group Distribution, Gharyan, Libya.
Mustafa Amran Abdulsalam Saieh, صالحة رجب, Omar Ali Saied Miftah, (05-2026), ليبيا: مجلة القلم - جامعة طرابلس الأهلية, 5 (9), 213-217
Assessment of Vitamin D Deficiency Prevalence A Field Laboratory Study in Gharyan City
Journal ArticleAbstract The prevalence of vitamin D deficiency has recently been recognized in different parts of the world, even affecting healthy populations. The deficiency of vitamin D can lead to rickets in children and osteomalacia in adults. No studies have been done in Gharyan city to evaluate the status of vitamin D among the population. So, this work aims to estimate the prevalence of vitamin D deficiency in the city, which is essential to maintaining the health of populations in general. This was a survey study conducted from September 2024 to December 2024, at some laboratories in the city: Alkama. Alnahda, Ayouser, Aldaka and Mashfa Gharyian. During the study period, 1718 analysis tests results of vitamin D were collected, classified to six groups according to age and characterized by measures of central tendency. The results showed that the age of the cases ranged from newborns to about 97 years, 30% males and 70 % females. Prevalence of vitamin D deficiency among female was more than males in all aged groups of the cases, about 62 % of the cases had low vitamin D levels (less than 30 ng/ml), the high level was 0.45% and 37% were at normal range. But the patients in categories 4, 5 had the highest number of cases. Spreading awareness among the population about the importance and vital role of the vitamin, explaining the risks of vitamin D deficiency and associated diseases among the population were recommended to reduce the Prevalence of vitamin D deficiency in Gharyan city
Mustafa Amran Abdulsalam Saieh, Yousuf A.K Aljetlawi, Omar Ali Saied Miftah, (02-2026), ليبيا: مجلة جامعة بني وليد للعلوم التطبيقية والإنسانية, 1 (11), 171-177
Antioxidant Activity of Natural Chamomile and Commercial Chamomile in Libya: A Comparative Study
Journal ArticleChamomile (Matricaria chamomilla L.) is a medical plant known for its antioxidant properties, which are attributed to bioactive compounds such as flavonoids and terpenoids. The study aimed to compare the antioxidant efficacy of natural chamomile with three commercial brands, A (Italian chamomile (Sonny)), B (Italian chamomile (Restora)), and C (German chamomile (UTZ)) available in Libyan markets. Methanol extracts of all samples were prepared by maceration, and antioxidant activity was evaluated using the DPPH radical scavenging assay. All data were expressed as mean ± standard deviation (SD). Statistical analysis was performed using one-way ANOVA, with A p-value < 0.05, which was considered statistically significant. Results revealed significant differences in IC50 values, with natural chamomile exhibiting the highest potency (IC50 = 3.35 mg/ml ± 0.055), followed by Brand A (IC50= 3.56 mg/ml ± 0.04) and Brand C (3.88 mg/ml ± 0.21). Brand B showed the weakest activity (IC50= 5.01 mg/ml ± 0.04). The statistical analysis confirmed the superiority of natural chamomile over commercial variants. Our findings suggest that processing methods, storage conditions, or potential additives in commercial products may degrade bioactive compounds, reducing antioxidant efficacy. This study highlights the advantage of minimally processed natural chamomile for optimal antioxidant benefits, and it underscores the implications for consumer choice and quality control in the manufacturing of herbal products.
ASHRAF AHMAD ISSA ALAPID, (05-2025), Libyan Medical Journal: Libyan Medical Journal, 2 (17), 205-209
Correlational study of vitamin D deficiency and dyslipidemia among adult Libyan population
Journal ArticleAbstract: Vitamin D deficiency is a public health concern affecting many individuals as it is highly prevalent in
all parts of the world. Recent studies have reported an association of vitamin D deficiency with cardiometabolic
alterations such as dyslipidemia. The study aimed to evaluate vitamin D and lipid profile levels among the Libyan
adult population and investigate the correlation of vitamin D deficiency with the alteration of lipid profile levels.
A cross-sectional study was conducted at Janzour Hospital among 193 subjects (107 males and 86 females) whose
ages ranged between 20 and 50 years over three months from Sept to Dec 2023. Vitamin D, cholesterol,
triglyceride, low-density lipoprotein, and high-density lipoprotein levels were estimated. The total mean vitamin
D levels were 8.31±4.74, 23.83±2.78, and 42.67±7.95 ng/dl for deficiency, insufficiency, and sufficiency,
respectively. The findings revealed significant alterations in cholesterol (increase), triglyceride (increase), LDLcholesterol
(increase), and HDL-cholesterol (decrease) among subjects who had vitamin D deficiency or
insufficiency as compared to subjects having vitamin D sufficiency. Vitamin D levels were negatively correlated
with cholesterol, triglyceride, and LDL cholesterol, and they were positively associated with HDL cholesterol.
The incidence of dyslipidemia is higher in the vitamin D deficiency group than in the insufficiency and sufficiency
groups. It is essential to frequently monitor lipid profiles among vitamin D-deficient individuals to avoid
subsequent disorders or damages associated with the alterations of lipid profile patterns.
ASHRAF AHMAD ISSA ALAPID, (05-2025), Mediterranean Journal of Pharmacy & Pharmaceutical Sciences: Mediterranean Journal of Pharmacy & Pharmaceutical Sciences, 2 (5), 96-103
Hypomagnesaemia and Relationship Lipid Profile in Type 2 Diabetes Patients at Janzur Hospital in Libya
Journal Article
ASHRAF AHMAD ISSA ALAPID, (11-2024), Alapid et al. Alq J Med App Sci: Alapid et al. Alq J Med App Sci, 7 (4), 973-979
تأثير دواء الكابوتين على مرضى غسيل الكلى
كتاباحمد فرج التومي عبد الرحمن، عمر علي سعيد مفتاح، (10-2022)، الاصابعة: مجلة القلم المبين،
تقدير بعض المعادن الثقيلة في التوابل الموجودة في السوق المحلي
مقال في مجلة علميةاحمد فرج التومي عبد الرحمن، عادل المبروك سعد ارحومه، (03-2022)، جامعة بني وليد: مجلة رواق الحكمة، 0
دراسة تطبيقية بمستشفى الاصابعة العام لمدى انتشار مرض الحمى المالطية
مقال في مؤتمر علمياحمد فرج التومي عبد الرحمن، مصطفى عمران عبدالسلام السائح، (10-2021)، الاصابعة: المعهد العالى للمهن الشاملة الاصابعة،